Description

N-[2-[(2R)-5α-(4-Formyl-2,3-dihydro-2-oxo-1H-imidazol-1-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-homoserine is a complex, high-purity synthetic organic compound with a defined stereochemistry, designed for advanced research and development applications. This compound is valued for its role as a key intermediate or building block in the synthesis of novel bioactive molecules, particularly in pharmaceutical discovery. It is primarily targeted at pharmaceutical R&D laboratories, biotechnology firms, and academic research institutions engaged in medicinal chemistry and drug development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential new chemical entities (NCEs) for drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity.
• Peptidomimetic Development: Acts as a sophisticated scaffold for creating peptide-like molecules with enhanced stability and bioavailability.
• Enzyme Inhibitor Synthesis: Potential precursor in the development of targeted enzyme inhibitors due to its complex heterocyclic and amino acid-derived structure.
• Chemical Biology Probes: Can be utilized to create specialized probes for studying biological pathways and protein interactions.
• Process Chemistry Development: Used in scaling up synthetic routes for advanced pharmaceutical intermediates under GMP-like conditions.

Basic Information

Product Name	N-[2-[(2R)-5α-(4-Formyl-2,3-dihydro-2-oxo-1H-imidazol-1-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-homoserine
CAS No.	95259-48-6
Molecular Formula	C27H35N7O11
Molecular Weight	633.61 g/mol
Synonyms	L-Homoserine, N-[2-[(2R)-5α-(4-formyl-2,3-dihydro-2-oxo-1H-imidazol-1-yl)tetrahydro-3β,4β-dihydroxy-2α-furanyl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-L-valyl]-L-glycyl]-; 95259-48-6; (2S)-2-[[(2S)-2-[[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino]acetyl]amino]-4-hydroxybutanoic acid - (2R,3R,4R,5R)-5-(4-formyl-2,5-dioxoimidazolidin-1-yl)-3,4-dihydroxytetrahydrofuran-2-carboxylic acid (1:1); Advanced Pharmaceutical Intermediate 95259-48-6; Complex Amino Acid Derivative
EINECS	Contact for details

Quality Control

Our N-[2-[(2R)-5α-(4-Formyl-2,3-dihydro-2-oxo-1H-imidazol-1-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-homoserine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.