Description

(2R,6S,7S,9R)-2α-[(1S,4S)-4-(3-Hydroxyphenyl)-4-methoxy-1-methylbutyl]-3β,9,11,11-tetramethyl-8-oxo-1-oxaspiro[5.5]undec-4-ene-7-carboxylic acid (3R)-tetrahydro-5-oxofuran-3-yl ester is a complex, high-purity synthetic intermediate characterized by its intricate spirocyclic and esterified structure. This compound is of significant value in advanced pharmaceutical research and development, particularly for its potential role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially for complex target molecules.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the development and scale-up of synthetic routes for new chemical entities under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development, quality control, and regulatory submissions.
• Academic Research: Utilized in university and institutional laboratories for studying complex organic reactions, stereochemistry, and total synthesis projects.
• Bioconjugation & Prodrug Synthesis: Its ester and hydroxyl functionalities make it a candidate for designing prodrugs or conjugates to improve drug delivery and pharmacokinetics.

Basic Information

Product Name	(2R,6S,7S,9R)-2α-[(1S,4S)-4-(3-Hydroxyphenyl)-4-methoxy-1-methylbutyl]-3β,9,11,11-tetramethyl-8-oxo-1-oxaspiro[5.5]undec-4-ene-7-carboxylic acid (3R)-tetrahydro-5-oxofuran-3-yl ester
CAS No.	95069-53-7
Molecular Formula	C33H46O8
Molecular Weight	570.72 g/mol
Synonyms	Contact for details
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and MS to verify identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the supply of material suitable for research and development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.