Description

(1R,3S)-5-[2-[(1R,3aR,7aS)-1-[(2R,5S)-5-hydroxy-6-methyl-heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol is a high-purity, stereochemically defined synthetic intermediate of significant importance in advanced organic synthesis. Its complex, polycyclic structure with multiple chiral centers makes it a critical building block for the development of novel bioactive compounds. This compound is primarily sought by pharmaceutical R&D and fine chemical sectors for the synthesis of complex molecules, including potential drug candidates and reference standards.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of novel therapeutic agents, particularly in steroid-like or complex terpenoid-based drug discovery programs.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex polycyclic frameworks in academic and industrial research laboratories.
• Reference Standard: Used as a high-purity analytical standard for method development, quality control, and regulatory submissions in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating enzyme-substrate interactions, receptor binding, and other biochemical pathways due to its specific stereochemistry.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of specialty chemicals, fragrances, and other high-value, structurally complex products.

Basic Information

Item	Detail
Product Name	(1R,3S)-5-[2-[(1R,3aR,7aS)-1-[(2R,5S)-5-hydroxy-6-methyl-heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol
CAS No.	93129-94-3
Molecular Formula	C30H46O3
Molecular Weight	454.69 g/mol
Synonyms	Calcipotriol Impurity 1; (1R,3S)-5-[(E)-2-[(1R,3aR,7aS)-1-[(2R,5S)-5-Hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; (1R,3S,5Z,7E,22E)-9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol; A potential precursor/derivative of Calcipotriol/MC 903.
EINECS	Contact for details

Quality Control

Our (1R,3S)-5-[2-[(1R,3aR,7aS)-1-[(2R,5S)-5-hydroxy-6-methyl-heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.