Description

Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(8-methyl-1-oxononyl)amino-β-D-glucopyranosyl-42-O-α-D-mannopyranosyl- is a structurally complex glycopeptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial intermediate or reference standard for the synthesis and study of novel antimicrobial agents, particularly against resistant bacterial strains. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and manufacturers of high-purity active pharmaceutical ingredients (APIs) focused on next-generation antibiotic therapies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel glycopeptide antibiotics and the study of structure-activity relationships (SAR).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Antimicrobial Agent Development: Investigated for its potential activity against Gram-positive bacteria, including drug-resistant strains like MRSA and VRE.
• Biochemical Research: Employed in studies targeting bacterial cell wall biosynthesis, specifically as a probe for understanding peptidoglycan assembly inhibition.
• Process Chemistry: Acts as a critical building block in the multi-step synthesis of complex natural product derivatives for preclinical evaluation.

Basic Information

Product Name	Ristomycin A aglycone, 34-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-2-deoxy-2-(8-methyl-1-oxononyl)amino-β-D-glucopyranosyl-42-O-α-D-mannopyranosyl-
CAS No.	91032-26-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ristomycin A aglycone derivative; 22,31-Dichloro-7-demethyl-64-O-demethyl-19-deoxyristomycin A aglycone glycoside; Ristocetin-like glycopeptide; Antibiotic A 35512 derivative; Complex glycopeptide intermediate; Chlorinated ristomycin aglycone; (Additional synonyms available on request)
EINECS	Contact for details

Quality Control

Our Ristomycin A aglycone derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced as a research-grade chemical, our quality systems are designed to support development work that may lead to GMP-grade production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.