Description

(Z)-2-Methyl-2-butenoic acid (3aR)-7α-(acetyloxy)-2,3,3aβ,4,5,7,7aα,8a,8bβ,8cα-decahydro-4β-hydroxy-6,8aα-dimethyl-3-methylene-2-oxooxireno[2,3]azuleno[4,5-b]furan-5α-yl ester is a high-purity, complex sesquiterpene lactone derivative with significant potential in advanced organic synthesis and pharmaceutical research. This compound is valued for its intricate stereochemistry and functional groups, which make it a versatile and sophisticated chemical intermediate for constructing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Advanced Organic Synthesis: Used in complex multi-step syntheses to introduce specific stereocenters and functionalized ring systems.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies and library development.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of high-value target molecules.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(Z)-2-Methyl-2-butenoic acid (3aR)-7α-(acetyloxy)-2,3,3aβ,4,5,7,7aα,8a,8bβ,8cα-decahydro-4β-hydroxy-6,8aα-dimethyl-3-methylene-2-oxooxireno[2,3]azuleno[4,5-b]furan-5α-yl ester
CAS No.	90735-00-5
Molecular Formula	C22H28O7
Molecular Weight	404.46 g/mol
Synonyms	2-Methyl-2-butenoic acid, (3aR,4S,5R,7aS,8aS,8bR,8cR)-decahydro-4-hydroxy-3a,8a-dimethyl-5-[[(2Z)-2-methyl-2-butenoyl]oxy]methyl]-6-methylene-2-oxooxireno[2,3]azuleno[4,5-b]furan-7-yl ester; Parthenolide derivative; Parthenolide 7-acetate 10-angelate?; Germacranolide sesquiterpene lactone ester; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and purity for critical research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.