Description

CyclohexanecarboxaMide, 4,4-difluoro-N-[(1S)-3-[(1α,3α,5α)-3'-(1-Methylethyl)-2'-oxo-1'-[(tetrahydro-2H-pyran-4-yl)Methyl]spiro[8-azabicyclo[3.2.1]octane-3,4'-iMidazolidin]-8-yl]-1-phenylpropyl]- (9CI) is a sophisticated, high-purity organic compound designed for advanced research and development applications. This complex molecule is valued for its specific stereochemistry and functional groups, making it a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) or metabolic disorder research.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.
• Biochemical Research: Potential use as a tool compound for probing specific biological pathways or enzyme interactions in vitro.
• Custom Synthesis: A starting point for the custom synthesis of more complex, proprietary molecules for specialized client projects.

Basic Information

Product Name	CyclohexanecarboxaMide, 4,4-difluoro-N-[(1S)-3-[(1α,3α,5α)-3'-(1-Methylethyl)-2'-oxo-1'-[(tetrahydro-2H-pyran-4-yl)Methyl]spiro[8-azabicyclo[3.2.1]octane-3,4'-iMidazolidin]-8-yl]-1-phenylpropyl]- (9CI)
CAS No.	891824-47-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4,4-Difluoro-N-[(1S)-3-[(1α,3α,5α)-3'-(1-Methylethyl)-2'-oxo-1'-[(tetrahydro-2H-pyran-4-yl)methyl]spiro[8-azabicyclo[3.2.1]octane-3,4'-imidazolidin]-8-yl]-1-phenylpropyl]cyclohexanecarboxamide; 891824-47-8; Spiro[8-azabicyclo[3.2.1]octane-3,4'-imidazolidine] derivative; Cyclohexanecarboxamide, 4,4-difluoro-N-[(1S)-3-[(1α,3α,5α)-3'-(1-methylethyl)-2'-oxo-1'-[(tetrahydro-2H-pyran-4-yl)methyl]spiro[8-azabicyclo[3.2.1]octane-3,4'-imidazolidin]-8-yl]-1-phenylpropyl]-; (9CI)
EINECS	Contact for details

Quality Control

Our CyclohexanecarboxaMide derivative is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development and commercial projects with material suitable for research use and can supply material manufactured under GMP guidelines for advanced clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.