Description

((4R,5R)-(+)-O-[1-Benzyl-1-(5-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)-2-phenylethyl](diphenylphosphinite)(1,5-COD)iridium(I)tetrakis(3,5-bis(trifluoromethyl)phenyl)borate is a high-purity, chiral iridium-based organometallic complex designed for advanced asymmetric catalysis. This compound matters as a highly selective and efficient catalyst for enantioselective hydrogenation and other critical C-H activation reactions, enabling the synthesis of complex chiral molecules with high optical purity. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance catalysts for creating active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Chiral Ligand Precursor: Serves as a source of sophisticated chiral phosphinite ligands for constructing other transition metal catalysts.
• API (Active Pharmaceutical Ingredient) Manufacturing: Enables the production of single-enantiomer drugs for central nervous system, cardiovascular, and oncological therapies.
• Agrochemical Synthesis: Used in the creation of chiral herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Fine Chemical and Fragrance Production: Catalyzes the synthesis of chiral flavors, fragrances, and advanced material precursors.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Item	Details
Product Name	((4R,5R)-(+)-O-[1-Benzyl-1-(5-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)-2-phenylethyl](diphenylphosphinite)(1,5-COD)iridium(I)tetrakis(3,5-bis(trifluoromethyl)phenyl)borate
CAS No.	880262-16-8
Molecular Formula	C96H78BF24IrNO2P
Molecular Weight	~1972.37 g/mol
Synonyms	Iridium(I) (1,5-COD)(P-OP) Tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; (4R,5R)-Walphos-type Iridium Catalyst; Chiral Iridium Phosphinite Complex; (R,R)-Walphos Ir(I) BArF Salt; Asymmetric Hydrogenation Catalyst (Iridium); Ir(COD)((R,R)-Walphos) BArF; [Ir((R,R)-Walphos)(COD)]BArF
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized to confirm identity, purity, and catalytic performance. Certificates of Analysis (COA) are provided, detailing key parameters such as assay, chiral purity, and residual solvent content. We adhere to strict internal quality protocols to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. This material is strictly light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light should be avoided. For long-term storage, keep the sealed container in a freezer (-20°C).

Specification

Item	Specification
Appearance	Orange to red crystalline or amorphous solid
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Solvent Residue (GC)	Complies with ICH guidelines
Moisture Content (KF)	Max. 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.