Description

2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride is a high-purity, complex organic intermediate featuring a unique imidazoline-piperazine-morpholine scaffold. This compound is of significant value for pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules targeting specific receptors. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for use in lead optimization and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes during preclinical and clinical development phases.
• Biochemical Tool Compound: Potential use in biochemical assays to study enzyme inhibition or receptor-ligand interactions.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Item	Details
Product Name	2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride
CAS No.	870007-79-7
Molecular Formula	C44H49Cl2N5O4 • HCl
Molecular Weight	803.27 g/mol (Free base: 767.80 g/mol)
Synonyms	1-(4-Morpholinyl)-2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(tert-butyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]ethanone hydrochloride; (4S,5R)-1-[4-[2-(4-Morpholinyl)-2-oxoethyl]-1-piperazinyl]carbonyl-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazole hydrochloride; UNII-9WZ8L1I8V9; 9WZ8L1I8V9; A complex imidazoline derivative hydrochloride salt.
EINECS	Contact for details

Quality Control

Our 2-[4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Recommended storage temperature: 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.