Description

D-glycero-Pentonic acid, 2,3-dideoxy-3-[[(2S)-1-oxo-2-[[(phenylMethoxy)carbonyl]aMino]propyl]aMino]-5-O-(2,3,5,6-tetrafluorophenyl)-, 1,1-diMethylethyl ester, (4ξ)- (9CI) is a sophisticated, high-purity synthetic intermediate characterized by its complex molecular architecture, which includes a protected pentonic acid backbone and a tetrafluorophenyl ether group. This compound is of significant value in advanced pharmaceutical research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require highly specific, structurally complex intermediates for cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral building block in the multi-step synthesis of novel therapeutic agents, particularly in areas requiring fluorinated or complex carbohydrate-derived structures.
• Antiviral Drug Research: Potential precursor in the development of nucleoside/nucleotide analogs and other antiviral compounds, leveraging its modified sugar-like framework.
• Glycobiology & Glycochemistry: Used in the study and synthesis of complex carbohydrates, glycoconjugates, and glycomimetics for biological activity screening.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore new chemical spaces and optimize drug candidate properties.
• Process Chemistry Development: Serves as a standard or reference material for scaling up and optimizing synthetic routes in pilot plants and kilo-labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	D-glycero-Pentonic acid, 2,3-dideoxy-3-[[(2S)-1-oxo-2-[[(phenylMethoxy)carbonyl]aMino]propyl]aMino]-5-O-(2,3,5,6-tetrafluorophenyl)-, 1,1-diMethylethyl ester, (4ξ)- (9CI)
CAS No.	868565-58-6
Molecular Formula	C26H28F4N2O7
Molecular Weight	556.51 g/mol
Synonyms	tert-Butyl (4ξ)-2,3-dideoxy-3-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]-5-O-(2,3,5,6-tetrafluorophenyl)-D-glycero-pentonate; 1,1-Dimethylethyl (4ξ)-2,3-dideoxy-3-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]-5-O-(2,3,5,6-tetrafluorophenyl)-D-glycero-pentonate; D-glycero-Pentonic acid, 2,3-dideoxy-3-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]-5-O-(2,3,5,6-tetrafluorophenyl)-, 1,1-dimethylethyl ester; (9CI) CAS 868565-58-6; ZINC000068051759; tert-Butyl 2,3-dideoxy-3-[[(2S)-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]propyl]amino]-5-O-(2,3,5,6-tetrafluorophenyl)-D-glycero-pentonate; Advanced Pharmaceutical Intermediate 868565-58-6
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality management systems to ensure batch-to-batch consistency and purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key analytical parameters. While not compendial (USP/EP), our quality protocols are designed to meet the exacting standards of pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.