Description

2-Penten-1-one, 4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-, (2E,4R)- is a highly functionalized, stereochemically complex organic compound, primarily serving as a critical synthetic intermediate in advanced organic synthesis. Its intricate structure, featuring multiple protected hydroxyl groups and defined stereocenters, makes it invaluable for constructing complex molecular architectures with high precision. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel bioactive molecules and natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially steroids, vitamin D analogs, and other polycyclic therapeutic agents.
• Advanced Organic Synthesis: Used in multi-step synthetic routes requiring specific stereochemistry and functional group manipulation.
• Natural Product Synthesis: Serves as a precursor in the total synthesis of complex natural products with biological activity.
• Chemical Research & Development: A valuable tool for method development and exploring new chemical transformations in academic and industrial R&D labs.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Penten-1-one, 4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-, (2E,4R)-
CAS No.	866406-02-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one; 1-Cyclopropyl-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-(2E,4R)-2-penten-1-one; A key intermediate for Vitamin D analogs; TBS-protected steroid synthesis intermediate.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are available upon request. We adhere to strict quality management protocols suitable for GMP-aligned production environments for non-API intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize the risk of oxidation and degradation. Keep away from moisture, strong bases, and fluorides. For long-term storage, consider freezing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0% (Area %)
Assay	Contact for details
Water Content	≤ 0.5% (K.F.)
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.