Description

4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-, ethyl ester is a sophisticated, high-purity chemical intermediate designed for advanced pharmaceutical synthesis. This compound is critical for researchers and manufacturers developing next-generation therapeutic agents, particularly in targeted disease areas. It is primarily utilized by the pharmaceutical and biotechnology industries for the research and development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and the creation of new chemical entities in research laboratories.
• Preclinical & Clinical Research: Serves as a critical material for producing compounds used in pharmacological studies and toxicity assessments.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Process Chemistry: Employed in route scouting and scale-up studies for efficient and cost-effective API manufacturing processes.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic research.

Basic Information

Item	Details
Product Name	4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-, ethyl ester
CAS No.	832720-84-0
Molecular Formula	C31H26F5N3O4
Molecular Weight	599.55 g/mol
Synonyms	Ethyl 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-4-methyl-2,6-dioxo-3,6-dihydro-1(2H)-pyrimidinyl]-1-phenylethyl]amino]benzoate; 832720-84-0; (R)-Ethyl 4-((1-(5-(2-fluoro-3-methoxyphenyl)-3-((2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-yl)-2-phenylethyl)amino)benzoate; UNII-9Y5F4N5U6I; Benzoic acid, 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-, ethyl ester
EINECS	Contact for details

Quality Control

Our 4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-1-phenylethyl]amino]-, ethyl ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from incompatible materials such as strong acids and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.