Description

5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-methyl-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid is a sophisticated nucleoside analogue with a complex, multi-functional structure designed for high-precision biochemical applications. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel antiviral or anticancer nucleoside analogues.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways and nucleic acid biochemistry.
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-methyl-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid
CAS No.	89156-93-4
Molecular Formula	C20H25N5O9
Molecular Weight	479.44 g/mol
Synonyms	1-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,5-dideoxy-5-[[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methyl-1-oxobutyl]amino]-β-D-allofuranuronic acid; β-D-allofuranuronic acid derivative; Nucleoside analogue intermediate; CAS 89156-93-4; 5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-methyl-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid; (2S,3S,4S)-N-[5-Deoxy-1-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-β-D-allofuranuron-5-yl]-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanamide
EINECS	Contact for details

Quality Control

Our 5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-methyl-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.