Description

5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid is a complex, high-purity nucleoside analogue derivative with significant potential in advanced pharmaceutical research and development. This compound is valued for its intricate chiral structure, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer drugs, as well as in biochemical studies exploring enzyme inhibition and nucleotide metabolism.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate pathways involving nucleotide synthesis and modification.
• Preclinical Drug Development: Serves as a critical reference standard or starting material for the synthesis of potential drug candidates targeting viral polymerases or specific cellular enzymes.
• Academic Research: Employed in universities and research institutes for studying structure-activity relationships (SAR) of modified nucleosides.
• Process Chemistry: Used in the development and optimization of synthetic routes for complex, biologically active molecules.

Basic Information

Product Name	5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid
CAS No.	89156-92-3
Molecular Formula	C20H25N5O10
Molecular Weight	495.44 g/mol
Synonyms	1,5-Dideoxy-5-[[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-β-D-allofuranuronic acid; β-D-allofuranuronic acid, 5-[[(2S,3S,4S)-2-amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxo-1(2H)-pyrimidinyl]-1,5-dideoxy-; 89156-92-3; Modified Nucleoside Derivative; Complex Nucleoside Analogue Intermediate.
EINECS	Contact for details

Quality Control

Our 5-[[(2S,3S,4S)-2-Amino-4-hydroxy-4-(5-hydroxy-2-pyridinyl)-3-methyl-1-oxobutyl]amino]-1-[3,4-dihydro-5-(hydroxymethyl)-2,4-dioxopyrimidin-1(2H)-yl]-1,5-dideoxy-β-D-allofuranuronic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storing under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.