Description

N-[2-[(2R)-5α-(3,4-Dihydro-5-methyl-2,4-dioxopyrimidin-1(2H)-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-glutamic acid is a complex, high-purity nucleoside analog derivative designed for advanced pharmaceutical research and development. This compound is critical for its potential role in targeting specific enzymatic pathways, offering a valuable tool for drug discovery and biochemical studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel antiviral or anticancer therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside-based active pharmaceutical ingredients (APIs).
• Antiviral Research: Investigated for its potential application in the development of new antiviral agents targeting viral polymerases.
• Oncology Research: Used in preclinical studies for designing potential anticancer prodrugs or targeted therapies.
• Biochemical Tool Compound: Employed in enzymatic assays and as a substrate analog to study enzyme kinetics and inhibition mechanisms.
• Process Chemistry & Scale-up: Utilized in route scouting and optimization for the commercial-scale production of complex drug candidates.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	N-[2-[(2R)-5α-(3,4-Dihydro-5-methyl-2,4-dioxopyrimidin-1(2H)-yl)tetrahydro-3β,4β-dihydroxyfuran-2α-yl]-N-[(3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl]-L-glycyl]-L-glutamic acid
CAS No.	89156-90-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2R,3S,4S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(((3S,4S)-4-hydroxy-4-(5-hydroxypyridin-2-yl)-L-valyl)glycyl)glutamyloxymethyl)tetrahydrofuran-3,4-diol; Nucleoside Amino Acid Conjugate; Complex Nucleoside Derivative; 89156-90-1; 5-Methyluridine Amino Acid Derivative; Thymidine Analog Conjugate; Pyrimidine Nucleoside-Valine-Glycine-Glutamate Conjugate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We adhere to strict quality management systems suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.