Description

(Z)-1-[[(8S,9S,10R,11R,13R,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-11-yl]oxy]-2-diazonio-ethenolate is a highly specialized steroid-derived diazonium compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring a reactive diazonioethenolate moiety on a complex steroidal backbone, makes it invaluable for constructing novel chemical entities with precise stereochemistry. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drug candidates, particularly in oncology and endocrinology research.
• Advanced Organic Synthesis: Used in coupling reactions, cycloadditions, and as a precursor for generating carbenes or other reactive species under controlled conditions.
• Chemical Biology Probe Development: Enables the site-specific labeling or modification of biomolecules for mechanistic studies and target identification.
• Process Chemistry & Scale-up: Serves as a high-value intermediate in the development and optimization of synthetic routes for complex molecules at pilot and commercial scales.
• Academic & Industrial R&D: Essential reagent for methodological research in synthetic organic chemistry, exploring new reactions and catalytic cycles.

Basic Information

Product Name	(Z)-1-[[(8S,9S,10R,11R,13R,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-11-yl]oxy]-2-diazonio-ethenolate
CAS No.	86271-88-7
Molecular Formula	C23H28N2O4
Molecular Weight	396.48 g/mol
Synonyms	17β-Acetoxy-3-oxoandrosta-1,4-dien-2-diazoniumolate; 2-Diazo-17β-acetoxyandrosta-1,4-diene-3-one; 17β-Acetoxy-2-diazoandrosta-1,4-diene-3-one; 2-Diazoandrosta-1,4-diene-3,17-dione 17-acetate; Steroidal diazonium ethenolate; Androstadienedione diazonium acetate derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (Z)-1-[[(8S,9S,10R,11R,13R,14S,17S)-17-acetyl-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-11-yl]oxy]-2-diazonio-ethenolate is manufactured and handled under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and stability. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support development projects requiring compliance with cGMP or other regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) due to its light-sensitive and hygroscopic nature. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress and thermal stress. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.