Description

(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propano yl]amino]propanoyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-3-phe nylmethoxy-propanoic acid is a complex, high-purity synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical building block or intermediate for the synthesis of novel peptide-based therapeutics, enabling precise control over molecular structure and bioactivity. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and fine chemical manufacturers engaged in developing targeted drug candidates, particularly in oncology, endocrinology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step production of complex peptide-based active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used as a critical research chemical for screening, structure-activity relationship (SAR) studies, and the development of novel therapeutic peptides.
• Bioconjugation & Peptide Engineering: Acts as a specialized component for modifying peptides to enhance stability, bioavailability, or targeting specificity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in peptide manufacturing and regulatory submissions.
• Academic & Institutional Research: Utilized in university and research institute laboratories for biochemical studies and the exploration of new peptide functionalities.

Basic Information

Product Name	(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propano yl]amino]propanoyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-3-phe nylmethoxy-propanoic acid
CAS No.	86248-85-3
Molecular Formula	C33H39N5O8
Molecular Weight	633.70 g/mol
Synonyms	H-Tyr-D-Ala-Gly-Phe-Leu-OH (sequence-related analog); Boc-Tyr-D-Ala-Gly-Phe-Leu-OMe (protected derivative); (2S)-2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanamido]-3-(phenylmethoxy)propanoic acid; Tyrosine-D-Alanine-Glycine-Phenylalanine-Leucine derivative; Peptide derivative CAS 86248-85-3; Advanced peptide building block; Custom peptide intermediate
EINECS	Contact for details

Quality Control

Our (2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propano yl]amino]propanoyl]amino]acetyl]amino]-3-phenyl-propanoyl]amino]-3-phe nylmethoxy-propanoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic data, and our processes support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.