Description

Benzyl N-[(1R)-1-[[2,4-dibromo-6-[(cyclohexyl-methyl-amino)methyl]phenyl]carbamoyl]-2-[(2R)-2-[[2,4-dibromo-6-[(cyclohexyl-methyl-amino)methyl]phenyl]carbamoyl]-2-phenylmethoxycarbonylamino-ethyl]disulfanyl-ethyl]carbamate is a sophisticated, high-purity synthetic intermediate featuring a complex, symmetrical disulfide-linked structure. This compound is of significant value for its role in advanced pharmaceutical research, particularly in the development of novel therapeutic agents and as a key building block in peptide and protein chemistry. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors that require precise molecular scaffolds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, particularly those targeting specific protein-protein interactions.
• Peptide Mimetic Research: Used in the design and synthesis of peptide mimetics and constrained peptides due to its disulfide bridge, which can help stabilize secondary structures.
• Bioconjugation Chemistry: Acts as a specialized reagent for creating disulfide-linked conjugates in antibody-drug conjugate (ADC) research and other bioconjugation applications.
• Chemical Biology Probes: Employed in the development of chemical probes for studying enzyme function and cellular pathways.
• Process Chemistry Development: Used in scale-up and optimization studies for the production of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical suppliers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	Benzyl N-[(1R)-1-[[2,4-dibromo-6-[(cyclohexyl-methyl-amino)methyl]phenyl]carbamoyl]-2-[(2R)-2-[[2,4-dibromo-6-[(cyclohexyl-methyl-amino)methyl]phenyl]carbamoyl]-2-phenylmethoxycarbonylamino-ethyl]disulfanyl-ethyl]carbamate
CAS No.	86042-50-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Benzyl (2R)-2-[[(2R)-2-[[[2,4-dibromo-6-[(cyclohexylmethylamino)methyl]phenyl]amino]carbonyl]amino]-3-[[(2R)-2-[[[2,4-dibromo-6-[(cyclohexylmethylamino)methyl]phenyl]amino]carbonyl]amino]-3-(benzyloxycarbonylamino)-1-oxopropyl]disulfanyl]propanoate; 86042-50-4; Symmetrical Dibromo Disulfide Intermediate; N,N'-Disulfide-linked bis-carbamate derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical R&D and scale-up work. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity, purity, and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support compliance with cGMP and ISO 9001 standards for pharmaceutical ingredient manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Keep the container tightly sealed in a desiccator to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.