Description

1(2H)-Naphthalenone, octahydro-2,7-dihydroxy-3-((1R)-1-(hydroxymethyl) propyl)-4-((2Z)-3-hydroxy-1-oxo-2-propenyl)-2,4,5,7-tetramethyl-, (2S, 3R,4R,4aS,5R,7R,8aS)-rel- is a complex, stereochemically defined polyhydroxylated naphthalenone derivative that serves as a high-value chiral building block and intermediate in advanced organic synthesis. Its intricate structure, featuring multiple stereocenters and functional groups, makes it a critical precursor for the development of pharmaceuticals and specialty fine chemicals. This compound is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in complex molecule synthesis.
• Medicinal Chemistry Research: Used as a scaffold or precursor in drug discovery programs to explore structure-activity relationships (SAR) and create novel compound libraries.
• Process Chemistry Development: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for target molecules in pilot and commercial manufacturing.
• Fine Chemical Synthesis: Building block for the production of specialty chemicals, including advanced materials, agrochemicals, and high-performance additives.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in organic synthesis, catalysis, and stereochemistry.

Basic Information

Product Name	1(2H)-Naphthalenone, octahydro-2,7-dihydroxy-3-((1R)-1-(hydroxymethyl) propyl)-4-((2Z)-3-hydroxy-1-oxo-2-propenyl)-2,4,5,7-tetramethyl-, (2S, 3R,4R,4aS,5R,7R,8aS)-rel-
CAS No.	81210-11-9
Molecular Formula	C20H32O6
Molecular Weight	368.47 g/mol
Synonyms	rel-(2S,3R,4R,4aS,5R,7R,8aS)-Octahydro-2,7-dihydroxy-3-[(1R)-1-(hydroxymethyl)propyl]-4-[(2Z)-3-hydroxy-1-oxo-2-propen-1-yl]-2,4,5,7-tetramethyl-1(2H)-naphthalenone; Polyhydroxylated Naphthalenone Derivative; Chiral Naphthalenone Intermediate; CAS 81210-11-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.