Description

Methyl 5-[[(3S,5R,8R,9S,10S,13R,17S)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxycarbonylmethylcarbamoyl]pentanoate is a high-purity, complex steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis of novel therapeutic agents targeting hormone-related pathways. It is essential for research institutions and pharmaceutical companies engaged in the development of steroid-based drugs, including potential anti-inflammatory, anti-cancer, or endocrine therapies. Our supply ensures the stringent quality and consistency required for sensitive R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used as a reference standard or precursor in medicinal chemistry for exploring new drug candidates targeting steroid receptors.
• Biochemical Research: Employed in studies investigating steroid hormone biosynthesis, metabolism, and receptor interaction mechanisms.
• Process Development: Serves as a critical material for optimizing and scaling up synthetic routes in pilot plants and manufacturing settings.
• Analytical Standard: Utilized in analytical laboratories for method development, validation, and quality control testing via HPLC, LC-MS, or NMR.

Basic Information

Item	Detail
Product Name	Methyl 5-[[(3S,5R,8R,9S,10S,13R,17S)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxycarbonylmethylcarbamoyl]pentanoate
CAS No.	81072-22-2
Molecular Formula	C33H47NO8
Molecular Weight	585.73 g/mol
Synonyms	Methyl 5-({[(3S,5R,8R,9S,10S,13R,17S)-14-Hydroxy-10,13-dimethyl-17-(5-oxo-2,5-dihydrofuran-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy}carbonylmethylcarbamoyl)pentanoate; 3β-[(Methoxycarbonylmethyl)carbamoyl]propionyloxy-14β-hydroxy-17β-(5-oxo-2,5-dihydrofuran-3-yl)-5β-androstane; Steroid Furanone Derivative; 81072-22-2; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our methyl 5-[[(3S,5R,8R,9S,10S,13R,17S)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxycarbonylmethylcarbamoyl]pentanoate undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality systems are designed to meet the exacting standards of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from HPLC, NMR, and other relevant spectroscopic and chromatographic methods. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be incompatible with strong acids/organic solvents and strong alkali/organic solvents. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.