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(13α,17aα)-15β-(Acetyloxy)-1α,14β:21,23-diepoxy-3α-hydroxy-4,4-dimethyl-2α-(3-methyl-1-oxobutoxy)-16-oxo-D-homo-24-nor-17-oxa-6,7-seco-5β-chola-7,20,22-triene-6-carboxylic acid methyl ester CAS NO 80931-32-4


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CAS No.:80931-32-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(13α,17aα)-15β-(Acetyloxy)-1α,14β:21,23-diepoxy-3α-hydroxy-4,4-dimethyl-2α-(3-methyl-1-oxobutoxy)-16-oxo-D-homo-24-nor-17-oxa-6,7-seco-5β-chola-7,20,22-triene-6-carboxylic acid methyl ester is a high-purity, complex steroidal derivative with significant value in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on steroid-based drug discovery.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based drug candidates targeting hormonal pathways, inflammation, or metabolic disorders.
  • Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing to ensure product purity and consistency.
  • Biochemical Research: Employed in academic and industrial research to study steroid receptor interactions, enzyme inhibition, and metabolic pathways.
  • Process Chemistry Development: Serves as a model compound for optimizing complex multi-step synthetic routes in fine chemical production.
  • Active Pharmaceutical Ingredient (API) Synthesis: Potential precursor in the manufacture of specialized steroidal active ingredients for clinical use.

Basic Information

Item Details
Product Name (13α,17aα)-15β-(Acetyloxy)-1α,14β:21,23-diepoxy-3α-hydroxy-4,4-dimethyl-2α-(3-methyl-1-oxobutoxy)-16-oxo-D-homo-24-nor-17-oxa-6,7-seco-5β-chola-7,20,22-triene-6-carboxylic acid methyl ester
CAS No. 80931-32-4
Molecular Formula C₃₃H₄₂O₁₁
Molecular Weight 614.68 g/mol
Synonyms Methyl (13α,17aα)-15β-(acetyloxy)-1α,14β:21,23-diepoxy-3α-hydroxy-4,4-dimethyl-2α-(3-methyl-1-oxobutanoyloxy)-16-oxo-D-homo-24-nor-17-oxa-6,7-seco-5β-chola-7,20,22-triene-6-carboxylate; 6,7-Secochola-7,20,22-triene-6-carboxylic acid derivative; 24-Nor-17-oxachola derivative; CAS 80931-32-4; Steroidal D-homo lactone derivative; Advanced steroidal epoxide intermediate.
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Quality Control

Our (13α,17aα)-15β-(Acetyloxy)-1α,14β:21,23-diepoxy-3α-hydroxy-4,4-dimethyl-2α-(3-methyl-1-oxobutoxy)-16-oxo-D-homo-24-nor-17-oxa-6,7-seco-5β-chola-7,20,22-triene-6-carboxylic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 97.0%
Assay 95.0% - 102.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.5%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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