Description

(4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is a high-purity steroidal derivative of significant interest in advanced pharmaceutical research and development. Its complex, defined stereochemistry makes it a valuable key intermediate for synthesizing novel therapeutic agents targeting hormone-related pathways. This compound is essential for R&D laboratories and pharmaceutical manufacturers engaged in the development of steroids and related bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates, particularly in endocrinology.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and impurity profiling of steroid products.
• Biochemical Research: Utilized in studies investigating steroid hormone biosynthesis, metabolism, and receptor interactions.

Basic Information

Item	Details
Product Name	(4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
CAS No.	80434-32-8
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	3β,17β-Dihydroxy-5α-androstane-17β-carboxylic acid; 17β-Carboxy-5α-androstane-3β,17β-diol; 5α-Androstane-3β,17β-diol-17β-carboxylic acid; 17β-Hydroxy-5α-androstan-3β-ylacetic acid; (3β,5α,17β)-3,17-Dihydroxyandrostane-17-carboxylic acid; A ring-modified steroidal acid intermediate
EINECS	Contact for details

Quality Control

Our (4R)-4-[(3S,5R,8S,9S,10S,12S,13R,14S)-1,3,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.