Description

2-Piperidinecarboxylic acid, 1-[2-oxo-2-[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14-hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen-1-yl]-3-methyl-2H-pyran-2-yl]acetyl]-, (2S)- is a complex, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel, structurally sophisticated active pharmaceutical ingredients (APIs), particularly in the fields of oncology and infectious diseases. It is essential for research institutions and pharmaceutical manufacturers engaged in the discovery and process development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of complex macrocyclic or polyene-based drug candidates.
• Anticancer Research: Used in the development and study of novel chemotherapeutic agents targeting specific cellular pathways.
• Antifungal/Antibiotic Development: Serves as a core structural component for creating new classes of antimicrobial compounds.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and cGMP manufacturing for clinical trial material.
• Chemical Biology: Utilized as a molecular probe or tool compound for studying enzyme mechanisms and protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical innovators.

Basic Information

Product Name	2-Piperidinecarboxylic acid, 1-[2-oxo-2-[(2R,3R,6S)-tetrahydro-2-hydroxy-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14-hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen-1-yl]-3-methyl-2H-pyran-2-yl]acetyl]-, (2S)-
CAS No.	763911-41-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2S)-1-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,19Z,21R)-14-Hydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15,19-docosapentaen-1-yl]-2-hydroxy-3-methyltetrahydro-2H-pyran-2-carbonyl]-2-oxo-2-piperidinecarboxylic acid; Advanced Polyketide Intermediate; Complex Macrocyclic Lactone Derivative; Pharmaceutical Building Block 763911-41-7.
EINECS	Contact for details

Quality Control

This high-value intermediate is produced under strict quality management systems to ensure batch-to-batch consistency and integrity. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and chiral purity. Certificates of Analysis (COA) detailing all critical quality attributes are provided with each shipment. We support development from milligram to kilogram scale with a commitment to cGMP-compliant practices where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as specified on the label. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert atmosphere packing.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.