Description

3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-7-[4-[[[4,5,6,7,8,9-hexahydro-3-(Methoxycarbonyl)cycloocta[b]thien-2-yl]aMino]thioxoMethyl]-1-piperazinyl]-1,4-dihydro-4-oxo- is a complex, high-purity pharmaceutical intermediate designed for advanced synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the construction of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical manufacturers and advanced research institutions engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinolone and fluoroquinolone-based active pharmaceutical ingredients (APIs).
• Antibacterial Agent Research: Serves as a core structural component in the development of next-generation antibacterial compounds targeting resistant pathogens.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of specialized, non-commercial drug candidates.
• Biochemical Research: Potential use as a tool compound for studying bacterial enzyme inhibition and related biochemical pathways.

Basic Information

Product Name	3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-7-[4-[[[4,5,6,7,8,9-hexahydro-3-(Methoxycarbonyl)cycloocta[b]thien-2-yl]aMino]thioxoMethyl]-1-piperazinyl]-1,4-dihydro-4-oxo-
CAS No.	727667-67-6
Molecular Formula	C30H32FN5O5S2
Molecular Weight	625.73 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-[4-[[[4,5,6,7,8,9-hexahydro-3-(methoxycarbonyl)cycloocta[b]thien-2-yl]amino]thioxomethyl]-1-piperazinyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; GSK-2140944 Intermediate; GSK2140944 Precursor; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-((((3-(methoxycarbonyl)-4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl)amino)(thioxo)methyl)piperazin-1-yl)quinoline-3-carboxylic acid; 727667-67-6; GSK'2140944 Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.