Description

(1S,4S,5aS,6R,9aR,10S)-1-[(S)-2-Acetoxy-2-(3-furyl)ethyl]-5a-(acetoxymethyl)-1,2,7,8,9,9a-hexahydro-2-hydroxy-10-methylspiro[1,4-methano-3-benzoxepine-6(4H),2'-oxiran]-5(5aH)-one is a complex, high-purity organic compound with a unique spirocyclic and oxirane structure. This compound is a critical advanced pharmaceutical intermediate or reference standard, valued for its precise stereochemistry and functional groups that enable sophisticated synthetic pathways. It is essential for research and development laboratories in the pharmaceutical and fine chemical sectors focused on novel active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in R&D and manufacturing.
• Organic Synthesis Research: Serves as a precursor for exploring new chemical entities (NCEs) and novel reaction methodologies in academic and industrial labs.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules.
• Biochemical Research: Potential use in studying enzyme interactions or as a ligand due to its specific three-dimensional conformation.

Basic Information

Item	Details
Product Name	(1S,4S,5aS,6R,9aR,10S)-1-[(S)-2-Acetoxy-2-(3-furyl)ethyl]-5a-(acetoxymethyl)-1,2,7,8,9,9a-hexahydro-2-hydroxy-10-methylspiro[1,4-methano-3-benzoxepine-6(4H),2'-oxiran]-5(5aH)-one
CAS No.	77984-53-3
Molecular Formula	C24H28O9
Molecular Weight	460.47 g/mol
Synonyms	1-[(2S)-2-Acetoxy-2-(3-furyl)ethyl]-5a-(acetoxymethyl)-1,2,7,8,9,9a-hexahydro-2-hydroxy-10-methylspiro[1,4-methano-3-benzoxepine-6(4H),2'-oxiran]-5(5aH)-one, (1S,4S,5aS,6R,9aR,10S)-; Spiro[1,4-methano-3-benzoxepine-6(4H),2'-oxiran] derivative; CAS 77984-53-3; 5aH-Spiro[1,4-methano-3-benzoxepine-6(4H),2'-oxiran]-5-one, 1-[2-(acetyloxy)-2-(3-furanyl)ethyl]hexahydro-2-hydroxy-5a-(hydroxymethyl)-10-methyl-, (1S,2S,5aS,6R,9aR,10S)-rel-; Furan-containing spirocyclic oxirane intermediate.
EINECS	Contact for details

Quality Control

Our (1S,4S,5aS,6R,9aR,10S)-1-[(S)-2-Acetoxy-2-(3-furyl)ethyl]-5a-(acetoxymethyl)-1,2,7,8,9,9a-hexahydro-2-hydroxy-10-methylspiro[1,4-methano-3-benzoxepine-6(4H),2'-oxiran]-5(5aH)-one is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and purity meet exacting research-grade standards. A detailed Certificate of Analysis (COA) with chromatographic data is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.