Description

(13α,14S,17S)-1α,11β,12α-Triacetoxy-21,23-epoxy-14-hydroxy-4a,4a-dimethyl-3,15-dioxo-A-homo-24-nor-4-oxa-6,7-seco-5α-chola-7,20,22-triene-6-carboxylic acid methyl ester is a highly functionalized, complex steroidal derivative with a unique seco-ring structure. This compound serves as a critical advanced intermediate in the synthesis of novel pharmaceutical agents, particularly in the research and development of steroid-based therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based drugs targeting hormonal regulation, inflammation, or metabolic pathways.
• Research & Development: Used in medicinal chemistry programs to explore structure-activity relationships (SAR) and develop new chemical entities (NCEs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex steroidal molecules.
• Biochemical Research: Potential tool compound for studying steroid receptor interactions and enzyme inhibition in biological systems.

Basic Information

Item	Details
Product Name	(13α,14S,17S)-1α,11β,12α-Triacetoxy-21,23-epoxy-14-hydroxy-4a,4a-dimethyl-3,15-dioxo-A-homo-24-nor-4-oxa-6,7-seco-5α-chola-7,20,22-triene-6-carboxylic acid methyl ester
CAS No.	77902-48-8
Molecular Formula	C₃₂H₄₀O₁₂
Molecular Weight	616.66 g/mol
Synonyms	Methyl (13α,14S,17S)-1α,11β,12α-triacetoxy-21,23-epoxy-14-hydroxy-4a,4a-dimethyl-3,15-dioxo-A-homo-24-nor-4-oxa-6,7-seco-5α-chola-7,20,22-triene-6-carboxylate; 6,7-Seco-5α-chola-7,20,22-triene-6-carboxylic acid derivative; 24-Nor-4-oxa-A-homo-cholane triacetate epoxide methyl ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (13α,14S,17S)-1α,11β,12α-Triacetoxy-21,23-epoxy-14-hydroxy-4a,4a-dimethyl-3,15-dioxo-A-homo-24-nor-4-oxa-6,7-seco-5α-chola-7,20,22-triene-6-carboxylic acid methyl ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.