Description

(1aR,7bS)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-ol is a complex, high-purity diterpenoid derivative with a unique polycyclic framework. This compound is valued for its role as a critical advanced synthetic intermediate in the development of novel pharmaceutical and agrochemical actives. It is primarily sought by R&D chemists and process development teams in the fine chemical, pharmaceutical, and life science research sectors for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides with complex mode-of-action targets.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study biological pathways and protein interactions.
• Asymmetric Synthesis: Utilized as a chiral starting material or intermediate in stereoselective synthesis due to its defined stereocenters.
• Material Science Research: Potential precursor for specialized organic materials and liquid crystals.
• Academic & Industrial R&D: Fundamental research compound in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	(1aR,7bS)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-ol
CAS No.	77646-27-6
Molecular Formula	C30H44O5
Molecular Weight	484.67 g/mol
Synonyms	15-Hydroxy-1,1,6,6,9,9,11,13α-octamethyl-1aα,2,7aα,13,14,14aα-hexahydro-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin; Diterpenoid Dioxin Derivative; Polycyclic Diterpene Alcohol; Advanced Synthetic Intermediate 77646-27-6; Complex Fused-Ring Alcohol; CAS 77646-27-6
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.