Description

(6R)-12α-Acetyloxy-6,6aβ,7aβ,8,9,12,12a,12bβ-octahydro-12aα-hydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one is a highly complex, polycyclic diterpenoid derivative with a unique and intricate molecular architecture. This compound serves as a critical advanced intermediate in the synthesis of high-value, biologically active molecules, particularly within pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on novel therapeutic agents, especially in areas requiring sophisticated chemical scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for complex natural product derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents with targeted biological activity.
• Process Chemistry Development: Serves as a pivotal intermediate for scaling up synthetic routes to complex active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Utilized in chemical biology and synthetic methodology research due to its challenging stereochemistry and ring system.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(6R)-12α-Acetyloxy-6,6aβ,7aβ,8,9,12,12a,12bβ-octahydro-12aα-hydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one
CAS No.	77573-46-7
Molecular Formula	C28H38O6
Molecular Weight	470.60 g/mol
Synonyms	12α-Acetoxy-6,6aβ,7aβ,8,9,12,12a,12bβ-octahydro-12aα-hydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d][1,3]dioxin-13-one; CAS 77573-46-7; A derivative of 6,6aβ,7aβ,8,9,12,12a,12bβ-octahydro-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d][1,3]dioxin-13-one; Polycyclic diterpenoid dioxin derivative.
EINECS	Contact for details

Quality Control

Our (6R)-12α-Acetyloxy-6,6aβ,7aβ,8,9,12,12a,12bβ-octahydro-12aα-hydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and related substances are provided and available upon request, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.