Description

(6R)-6,6aβ,7aβ,8,9,12,12a,12bβ-Octahydro-12α,12aα-dihydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one is a high-purity, complex diterpenoid derivative with a unique polycyclic framework. This compound is valued as a critical advanced intermediate in the synthesis of novel bioactive molecules, particularly within pharmaceutical research. It serves the needs of R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel diterpenoid-based drug candidates.
• Medicinal Chemistry Research: Used in R&D for exploring new chemical entities (NCEs) and structure-activity relationship (SAR) studies.
• Organic Synthesis: Serves as a complex starting material or intermediate for synthesizing natural product analogs and other polycyclic compounds.
• Biochemical Research: Potential use as a probe or ligand in studying biological pathways and enzyme interactions.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(6R)-6,6aβ,7aβ,8,9,12,12a,12bβ-Octahydro-12α,12aα-dihydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one
CAS No.	77573-43-4
Molecular Formula	C24H34O5
Molecular Weight	402.53 g/mol
Synonyms	13-Oxomanoyl Oxide; 13-Oxo-manoyl oxide; 13-Oxomanoyloxide; 13-Oxo-8(17),14-labdadien-18-oic acid derivative; Diterpenoid 77573-43-4; Labdane diterpene derivative; (6R,6aR,7aS,9R,9aS,12R,12aR,12bS)-12,12a-Dihydroxy-2,2,7,7,9,11-hexamethyl-6,6a,7,7a,8,9,12,12a,12b,13-decahydro-4H-6,9a-methanocyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d][1,3]dioxin-13-one
EINECS	Contact for details

Quality Control

Our (6R)-6,6aβ,7aβ,8,9,12,12a,12bβ-Octahydro-12α,12aα-dihydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and potential degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.