Description

(1aR,2R,3S,4aR,6S,7S,7aS,8E,10R,11R,11aS)-2,7,10-Tris(acetyloxy)-1a,2,3,6,7,10,11,11a-octahydro-11-methoxy-1,1,3,6,9-pentamethyl-4a,7a-epoxy-5H-cyclopenta[a]cyclopropa[f]cycloundecen-4(1H)-one is a complex, high-purity sesquiterpene lactone derivative with significant biological activity. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile scaffold for medicinal chemistry research. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel anti-inflammatory, anti-cancer, or anti-infective drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Tool Compound: Employed in biological assays to study specific cellular pathways and mechanisms of action.
• Agrochemical Research: Investigated as a precursor for developing new plant protection agents with novel modes of action.
• Academic & Institutional R&D: Utilized in university and research institute projects focused on natural product synthesis and derivatization.

Basic Information

Product Name	(1aR,2R,3S,4aR,6S,7S,7aS,8E,10R,11R,11aS)-2,7,10-Tris(acetyloxy)-1a,2,3,6,7,10,11,11a-octahydro-11-methoxy-1,1,3,6,9-pentamethyl-4a,7a-epoxy-5H-cyclopenta[a]cyclopropa[f]cycloundecen-4(1H)-one
CAS No.	77573-15-0
Molecular Formula	C28H38O9
Molecular Weight	518.60 g/mol
Synonyms	Artemisinin derivative; Arteannuin B triacetate; Qinghaosu derivative; 11-Methoxyarteannuin B triacetate; (8E)-11-Methoxyarteannuin B 2,7,10-triacetate; 3,12-Epoxy-4,11-dihydroxy-6,15-dimethylandrosta-1,8-dien-17-one 4,11-diacetate (related structural description); Contact for additional IUPAC or trade names.
EINECS	Contact for details

Quality Control

We supply this advanced intermediate under a rigorous quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results from analytical techniques such as HPLC, NMR, and MS. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical starting materials, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.