Description

(1aR)-5β,6β-Bis(benzoyloxy)-1aα,2,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-(hydroxymethyl)-1,1,7,9α-tetramethyl-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one is a complex diterpenoid derivative with a highly functionalized, multi-ring core structure. This compound serves as a critical advanced intermediate in the synthesis of high-value, biologically active molecules, particularly within pharmaceutical research and development. It is essential for chemists and organizations engaged in the synthesis of novel therapeutic agents, especially those targeting complex biochemical pathways.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new chemical entities with optimized biological profiles.
• Process Chemistry Development: Serves as a benchmark or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in API (Active Pharmaceutical Ingredient) manufacturing.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring new synthetic methodologies and reaction mechanisms involving complex polycyclic systems.
• Biochemical Probe Development: Acts as a precursor for creating labeled compounds or probes used in mechanistic biological studies.

Basic Information

Item	Details
Product Name	(1aR)-5β,6β-Bis(benzoyloxy)-1aα,2,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-(hydroxymethyl)-1,1,7,9α-tetramethyl-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one
CAS No.	77495-85-3
Molecular Formula	C34H40O7
Molecular Weight	560.68 g/mol
Synonyms	5β,6β-Dibenzoyloxy-1aα,2,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-(hydroxymethyl)-1,1,7,9α-tetramethyl-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one; (1aR,2S,4S,5aR,6S,8aR,9S,10aR)-5β,6β-Bis(benzoyloxy)-1aα,2,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-(hydroxymethyl)-1,1,7,9α-tetramethyl-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one; Taxinine J derivative; Diterpenoid benzoyl ester intermediate.
EINECS	Contact for details

Quality Control

Our (1aR)-5β,6β-Bis(benzoyloxy)-1aα,2,5,5a,6,9,10,10aα-octahydro-5aβ-hydroxy-4-(hydroxymethyl)-1,1,7,9α-tetramethyl-1H-2α,8aα-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure structural identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.