Description

2-[2-[2-[[6-amino-2-[1-[(2-amino-2-carbamoyl-ethyl)amino]-2-carbamoyl-ethyl]-5-methyl-pyrimidine-4-carbonyl]amino]-2-[[4-[[1-[[1-(5-amino-3,4-dihydroxy-6-methyl-oxan-2-yl)oxy-2-[4-[4-[[4-amino-5-(3-methylaminopropylcarbamoyl)pentyl]carbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-2-hydroxy-ethyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-3-hydroxy-butan-2-yl]carbamoyl]-1-(3H-imidazol-4-yl)ethoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate is a complex, high-purity biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its intricate molecular architecture, which serves as a critical building block for synthesizing novel therapeutic agents. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of next-generation drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Bioconjugation Research: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive functional groups.
• Enzyme Inhibitor Development: Acts as a scaffold for designing and testing novel enzyme inhibitors, leveraging its structural similarity to natural cofactors or substrates.
• Chemical Biology Probes: Employed in the creation of molecular probes to study specific biochemical pathways and protein interactions within cells.
• Peptidomimetic Synthesis: Used as a non-standard amino acid analog in the synthesis of peptidomimetics to enhance stability and bioavailability of peptide-based drugs.
• High-Value Fine Chemical Production: Integral to the custom synthesis of specialty chemicals for advanced material science and diagnostic applications.

Basic Information

Item	Details
Product Name	2-[2-[2-[[6-amino-2-[1-[(2-amino-2-carbamoyl-ethyl)amino]-2-carbamoyl-ethyl]-5-methyl-pyrimidine-4-carbonyl]amino]-2-[[4-[[1-[[1-(5-amino-3,4-dihydroxy-6-methyl-oxan-2-yl)oxy-2-[4-[4-[[4-amino-5-(3-methylaminopropylcarbamoyl)pentyl]carbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-2-hydroxy-ethyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]-3-hydroxy-butan-2-yl]carbamoyl]-1-(3H-imidazol-4-yl)ethoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
CAS No.	77368-67-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Vitamin B12 intermediate; Cobalamin precursor; Cobamide derivative; Complex biochemical carbamate; Research compound 77368-67-3; Advanced pharmaceutical building block; Cyanocobalamin analog intermediate; Corrinoid synthesis intermediate
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and tested under strict quality management systems to ensure consistency and purity for critical research applications. Our quality assurance includes comprehensive analytical characterization using HPLC, NMR, and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We adhere to cGMP guidelines where applicable to support our clients' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.