Description

(2aR,8aβ,8bα)-Decahydro-3α,5α-diacetoxy-7α-[(3R,5S)-5-acetoxy-3-(3-furyl)-2-methyl-1-cyclopenten-1-yl]-8α-benzoyloxy-2a,5aβ,7-trimethyl-2H-naphtho[1,8-bc]furan-6β-acetic acid methyl ester is a complex, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly within the steroid and terpenoid chemical space. It is essential for R&D chemists and process development scientists working on innovative drug candidates in oncology, endocrinology, and anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: Key precursor in the multi-step synthesis of novel steroid-mimetic drug candidates and complex natural product derivatives.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry: Serves as a defined starting material or intermediate in scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Academic Research: Valuable compound for studying complex organic synthesis methodologies, including stereoselective transformations.
• Bioconjugation & Prodrug Development: Potential use in designing targeted drug delivery systems due to its functionalizable ester and benzoyl groups.

Basic Information

Item	Details
Product Name	(2aR,8aβ,8bα)-Decahydro-3α,5α-diacetoxy-7α-[(3R,5S)-5-acetoxy-3-(3-furyl)-2-methyl-1-cyclopenten-1-yl]-8α-benzoyloxy-2a,5aβ,7-trimethyl-2H-naphtho[1,8-bc]furan-6β-acetic acid methyl ester
CAS No.	76689-95-7
Molecular Formula	C41H48O11
Molecular Weight	716.82 g/mol
Synonyms	Methyl (2aR,8aβ,8bα)-decahydro-3α,5α-diacetoxy-7α-[(3R,5S)-5-acetoxy-3-(3-furyl)-2-methyl-1-cyclopenten-1-yl]-8α-benzoyloxy-2a,5aβ,7-trimethyl-2H-naphtho[1,8-bc]furan-6β-acetate; 76689-95-7; 2H-Naphtho[1,8-bc]furan-6β-acetic acid, decahydro-3α,5α-diacetoxy-7α-[(3R,5S)-5-acetoxy-3-(3-furyl)-2-methyl-1-cyclopenten-1-yl]-8α-benzoyloxy-2a,5aβ,7-trimethyl-, methyl ester, (2aR,8aβ,8bα)-; Complex Steroidal Furan Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability for critical R&D and scale-up work. All batches are characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for assay, related substances, and residual solvents. We support development with custom synthesis and purification services to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.