Description

(Z)-2-Methyl-2-butenoic acid [(3aR,4R,6R,7S,9R,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-7,9-dihydroxy-10-hydroxymethyl-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl] ester is a complex, high-purity chemical intermediate with significant value in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly for constructing intricate molecular architectures. It serves as a key building block for medicinal chemists and process development scientists targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a key material for developing and scaling up synthetic routes in pilot plants and commercial manufacturing.
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex natural products and their analogs for biological evaluation.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or probes for biochemical and diagnostic research.
• Academic & Institutional Research: Supplied to universities and research institutes for cutting-edge chemical and biological studies.

Basic Information

Product Name	(Z)-2-Methyl-2-butenoic acid [(3aR,4R,6R,7S,9R,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-7,9-dihydroxy-10-hydroxymethyl-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl] ester
CAS No.	75680-26-1
Molecular Formula	C₂₁H₂₈O₈
Molecular Weight	408.45 g/mol
Synonyms	2-Methyl-2-butenoic acid (3aR,4R,6R,7S,9R,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-7,9-dihydroxy-10-hydroxymethyl-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester; Tiglic acid ester of a decahydro-epoxy-furan derivative; CAS 75680-26-1; (Z)-Tiglate derivative; (3aR,4R,6R,7S,9R,10Z,11aR)-4-[[(2Z)-2-Methylbut-2-enoyl]oxy]-2,3,3a,4,5,6,7,8,9,11a-decahydro-7,9-dihydroxy-10-(hydroxymethyl)-6-methyl-3-methylidene-2-oxo-6,9-epoxycyclodeca[b]furan
EINECS	Contact for details

Quality Control

Our (Z)-2-Methyl-2-butenoic acid ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency suitable for advanced research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and kept in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.