Description

(Z)-2-Methyl-2-butenoic acid [(3aR,4R,6S,9R,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-9-hydroxy-10-hydroxymethyl-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl] ester is a complex, high-purity sesquiterpene lactone derivative with significant biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable scaffold for medicinal chemistry research. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Natural Product Synthesis: Serves as a synthetic target or intermediate in the total synthesis of complex natural products with sesquiterpene lactone frameworks.
• Biochemical Probe Development: Utilized in the development of molecular probes to study specific biological pathways and protein interactions.
• Agrochemical Research: Investigated as a precursor for novel plant protection agents with potential insecticidal or fungicidal activity.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	(Z)-2-Methyl-2-butenoic acid [(3aR,4R,6S,9R,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-9-hydroxy-10-hydroxymethyl-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl] ester
CAS No.	75680-25-0
Molecular Formula	C21H28O7
Molecular Weight	392.45 g/mol
Synonyms	Alantolactone 4-Angelate; 4α-Angeloyloxy-1(10),11(13)-guaien-12,8α-olide; (4R)-4α-Angeloyloxy-1(10),11(13)-guaien-12,8α-olide; Isoalantolactone angelate; 1(10),11(13)-Guaien-12,8α-olide, 4α-(angeloyloxy)-, (4R)-; 8αH-3a,4,5,6,7,8,9,11a-Octahydro-9-hydroxy-10-(hydroxymethyl)-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl (2Z)-2-methyl-2-butenoate
EINECS	Contact for details

Quality Control

Our production of (Z)-2-Methyl-2-butenoic acid [(3aR,4R,6S,9R,10Z,11aR)-2,3,3a,4,5,6,7,8,9,11a-decahydro-9-hydroxy-10-hydroxymethyl-6-methyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl] ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.