Description

5-hydroxy-4-[(2S)-2-[(1R,2S,6R)-2-[(E)-3-hydroxy-2-[(2R,3R,6S)-6-[(E,3S)-3-[(3S,5R)-5-[(1S)-1-methoxyethyl]-3-methyl-oxolan-2-yl]but-1-enyl]-3-methyl-oxan-2-yl]prop-1-enyl]-6-methyl-cyclohexyl]propanoyl]furan-3-one is a complex, stereochemically defined macrolide derivative of significant interest in advanced organic synthesis. This compound matters as a high-value chiral building block and intermediate for the research and development of novel bioactive molecules. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on creating complex natural product analogs, specialty agrochemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel macrolide antibiotics and other complex therapeutic agents.
• Agrochemical Research: Used in developing advanced, stereospecific active ingredients for crop protection with potentially novel modes of action.
• Chemical Biology Probe: Serves as a sophisticated molecular scaffold for studying biological interactions and enzyme mechanisms.
• Asymmetric Synthesis: Employed as a critical starting material or intermediate in multi-step total synthesis projects requiring high stereochemical fidelity.
• Fine Chemical Manufacturing: Utilized in the production of high-value, low-volume specialty chemicals for research and niche industrial applications.

Basic Information

Product Name	5-hydroxy-4-[(2S)-2-[(1R,2S,6R)-2-[(E)-3-hydroxy-2-[(2R,3R,6S)-6-[(E,3S)-3-[(3S,5R)-5-[(1S)-1-methoxyethyl]-3-methyl-oxolan-2-yl]but-1-enyl]-3-methyl-oxan-2-yl]prop-1-enyl]-6-methyl-cyclohexyl]propanoyl]furan-3-one
CAS No.	75139-06-9
Molecular Formula	C31H48O8
Molecular Weight	548.71 g/mol
Synonyms	5-Hydroxy-4-[(2S)-2-[(1R,2S,6R)-2-[(E)-3-hydroxy-2-[(2R,3R,6S)-6-[(E,3S)-3-[(3S,5R)-5-[(1S)-1-methoxyethyl]-3-methyl-2-oxolanyl]but-1-enyl]-3-methyl-2-oxanyl]prop-1-enyl]-6-methylcyclohexyl]propanoyl]-3(2H)-furanone; (2S,3S,4R,6S,7R,9S,11S,12R,13S,14R,16E,18E,20R,21S,24R)-6-[(1S)-1-Methoxyethyl]-4,12,14-trihydroxy-5,7,9,11,13,21,24-heptamethyl-2-oxo-3,20-epoxy-1-oxacyclotetracos-16,18-dien-10-one; Macrolide derivative 75139-06-9; Complex Furanone Macrolide Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and chiral analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development projects requiring compliance with ICH guidelines for impurities and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.