Description

2-PIPERIDINECARBOXYLIC ACID, 1-[5-[IMINO(NITROAMINO)METHYL]AMINO]-2-[[(3-METHYL-8-QUINOLINYL)SULFONYL]AMINO]-1-OXOPENTYL]-4-METHYL-,ETHYL ESTER,[2R-[1(S*), 2ALPHA, 4BETA]]- is a complex, stereochemically defined synthetic organic compound featuring a piperidine core integrated with quinoline and nitroamino functional groups. This intricate molecular architecture makes it a high-value intermediate for advanced pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially in areas requiring sophisticated peptidomimetics or enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly for protease inhibitors or other enzyme-targeted therapies.
• Protease Inhibitor Research: The structural motifs suggest potential application in the development of inhibitors for specific proteases (e.g., thrombin, factor Xa), relevant for anticoagulant or antiviral drug discovery.
• Peptidomimetic Development: Used in medicinal chemistry to create peptidomimetics—molecules that mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probe: Acts as a specialized tool compound for studying enzyme function and signal transduction pathways in biochemical and cellular assays.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing organizations (CMOs) for producing high-purity, complex molecules for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis methodology and drug design principles.

Basic Information

Item	Details
Product Name	2-Piperidinecarboxylic acid, 1-[5-[imino(nitroamino)methyl]amino]-2-[[(3-methyl-8-quinolinyl)sulfonyl]amino]-1-oxopentyl]-4-methyl-, ethyl ester, [2R-[1(S*), 2alpha, 4beta]]-
CAS No.	74874-09-2
Molecular Formula	C25H36N6O7S
Molecular Weight	564.66 g/mol
Synonyms	Ethyl 1-[5-[(carbamimidoylnitroamino)methylamino]-2-[(3-methylquinolin-8-yl)sulfonylamino]-5-oxopentyl]-4-methylpiperidine-2-carboxylate; (2R,4S)-1-[(2S)-5-[(Carbamimidoylnitroamino)methylamino]-2-[(3-methylquinolin-8-yl)sulfonylamino]-5-oxopentyl]-4-methylpiperidine-2-carboxylic acid ethyl ester; A potential thrombin inhibitor intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity essential for research and development. Quality is verified through analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.