Description

[2R-[1(S),2alpha,4beta]]-1-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid ethyl ester is a sophisticated, high-purity chemical intermediate characterized by its complex, multi-functional molecular architecture. This compound is of significant value in advanced organic synthesis, particularly for constructing molecules with specific stereochemical configurations. It is primarily sought after by research institutions and pharmaceutical development teams engaged in the synthesis of novel therapeutic agents, including protease inhibitors and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the research and development of new drug candidates, especially those targeting enzymatic pathways.
• Protease Inhibitor Synthesis: Serves as a key precursor in the synthesis of complex molecules designed to inhibit specific proteases.
• Peptidomimetic Research: Used in the development of peptidomimetics—molecules that mimic peptides but with enhanced stability and bioavailability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological activity of lead compounds.
• Bioconjugation Chemistry: The reactive functional groups make it suitable for creating conjugates in biopharmaceutical research.
• Academic & Industrial R&D: Utilized in laboratories for methodological development in asymmetric synthesis and complex molecule construction.

Basic Information

Product Name	[2R-[1(S),2alpha,4beta]]-1-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid ethyl ester
CAS No.	74874-07-0
Molecular Formula	C21H37N5O7
Molecular Weight	471.55 g/mol
Synonyms	Ethyl (2R,4S)-1-[(2S)-2-[(tert-Butoxycarbonyl)amino]-5-[(carbamimidoylnitroamino)amino]-5-oxopentanoyl]-4-methylpiperidine-2-carboxylate; BOC-Protected Nitroguanidino Peptidomimetic Intermediate; tert-Butyl N-[(1S)-4-[[amino(nitroamino)methylidene]amino]-1-[(2R,4S)-2-(ethoxycarbonyl)-4-methylpiperidine-1-carbonyl]butyl]carbamate; (2R,4S)-1-[(2S)-2-(tert-Butoxycarbonylamino)-5-(nitroguanidino)-5-oxopentanoyl]-4-methylpiperidine-2-carboxylic acid ethyl ester; CAS 74874-07-0
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management systems. We employ state-of-the-art analytical techniques, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when being weighed or transferred to prevent degradation. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.