Description

(3aS,4S,5S,6E,10S,11aR)-5-Acetoxy-2,3,3a,4,5,8,9,10,11,11a-decahydro-10-hydroxymethyl-3-methylene-4-[(R)-2-methyl-1-oxobutoxy]-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester is a complex, high-purity synthetic intermediate with a defined stereochemistry. This compound is valued for its role as a key building block in advanced organic synthesis, particularly for the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of complex natural product derivatives and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially within complex macrocyclic or polyketide-derived compound libraries.
• Organic Synthesis Research: Serves as a versatile chiral building block for academic and industrial research into new synthetic methodologies and total synthesis projects.
• Natural Product Analog Development: Used to create synthetic analogs of complex natural products for structure-activity relationship (SAR) studies and bioactivity screening.
• Fine Chemical Production: Employed in the manufacture of high-value, specialized fine chemicals requiring precise stereochemical control.
• Biochemical Probe Synthesis: Utilized in the development of molecular probes for studying biological pathways and enzyme interactions.

Basic Information

Product Name	(3aS,4S,5S,6E,10S,11aR)-5-Acetoxy-2,3,3a,4,5,8,9,10,11,11a-decahydro-10-hydroxymethyl-3-methylene-4-[(R)-2-methyl-1-oxobutoxy]-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester
CAS No.	74562-66-6
Molecular Formula	C23H32O9
Molecular Weight	452.50 g/mol
Synonyms	Methyl (3aS,4S,5S,6E,10S,11aR)-5-Acetoxy-10-(hydroxymethyl)-3-methylene-4-[(2R)-2-methylbutanoyl]oxy-2-oxo-2,3,3a,4,5,8,9,10,11,11a-decahydrocyclodeca[b]furan-6-carboxylate; 74562-66-6; A derivative of Cyclodeca[b]furan-6-carboxylic acid; A complex macrocyclic furan ester intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality is verified through analytical methods including HPLC, NMR, and Mass Spectrometry. We operate under a cGMP-compliant quality management system to meet the exacting standards of pharmaceutical and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.