Description

(Z)-4-Hydroxy-2-methyl-2-butenoic acid [(1aR,3R,4Z,5aR,8aR,9R,10aR)-3-acetoxy-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester is a complex, high-purity organic ester derivative with significant potential in advanced chemical synthesis. This compound matters as a sophisticated chemical intermediate for research and development in specialized pharmaceutical and agrochemical applications. It is primarily needed by R&D chemists and process development teams in the fine chemical and life sciences industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel therapeutic agents, particularly in complex natural product-derived pathways.
• Agrochemical Research: Used in the development of new, high-efficacy active ingredients for crop protection products.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating specialized esters and other derivatives in custom synthesis projects.
• Academic & Industrial R&D: Employed in methodological studies and as a reference standard in chemical research exploring complex molecular architectures.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing production processes for advanced chemical entities.

Basic Information

Product Name	(Z)-4-Hydroxy-2-methyl-2-butenoic acid [(1aR,3R,4Z,5aR,8aR,9R,10aR)-3-acetoxy-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl] ester
CAS No.	72984-73-7
Molecular Formula	C24H30O8
Molecular Weight	446.49 g/mol
Synonyms	4-Hydroxy-2-methyl-2-butenoic acid (1aR,3R,4Z,5aR,8aR,9R,10aR)-3-acetoxy-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4,10a-dimethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester, (Z)-; Artemether Impurity F (EP); Artemether Related Compound F; 72984-73-7; Dihydroartemisinin 4-acetoxy-3-(4-hydroxy-2-methyl-2-butenoate); (3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl 4-acetoxy-3-(4-hydroxy-2-methylbut-2-enoate)
EINECS	Contact for details

Quality Control

Our (Z)-4-Hydroxy-2-methyl-2-butenoic acid ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and MS. We provide full traceability and Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. The product is suitable for use under cGMP conditions for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.