Description

(Z)-2-Methyl-2-butenoic acid [(3aS,9aS,9bS)-2,3,3a,5,6,9,9a,9b-octahydro-6β-hydroxy-6,9-dimethyl-3-methylene-2-oxo-4H-6aβ,9β-ethenofuro[2',3':3,4]cyclohepta[1,2-c][1,2]dioxol-5β-yl] ester is a high-purity, complex sesquiterpene lactone derivative with significant synthetic utility. This compound matters as a critical chiral building block and intermediate for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly in anti-inflammatory and anti-cancer research pipelines.
• Agrochemical Synthesis: Used as a sophisticated building block for developing advanced crop protection agents and bioactive molecules.
• Organic Synthesis Research: A valuable substrate for methodological studies in asymmetric synthesis, cycloaddition reactions, and natural product total synthesis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, flavors, and fragrances requiring complex stereochemistry.
• Reference Standard: Supplied as a certified analytical standard for quality control and research in laboratories.

Basic Information

Item	Detail
Product Name	(Z)-2-Methyl-2-butenoic acid [(3aS,9aS,9bS)-2,3,3a,5,6,9,9a,9b-octahydro-6β-hydroxy-6,9-dimethyl-3-methylene-2-oxo-4H-6aβ,9β-ethenofuro[2',3':3,4]cyclohepta[1,2-c][1,2]dioxol-5β-yl] ester
CAS No.	72690-44-9
Molecular Formula	C22H28O7
Molecular Weight	404.46 g/mol
Synonyms	Alantolactone Tiglate; (Z)-Alantolactone Tiglate; (Z)-Alantolactone Tigloyl Ester; (Z)-2-Methyl-2-butenoic acid alantolactone ester; (3aS,9aS,9bS)-2,3,3a,5,6,9,9a,9b-Octahydro-6β-hydroxy-6,9-dimethyl-3-methylene-2-oxo-4H-6aβ,9β-ethenofuro[2',3':3,4]cyclohepta[1,2-c][1,2]dioxol-5β-yl (Z)-2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our (Z)-2-Methyl-2-butenoic acid alantolactone ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.