Description

6-O-(4-C-Methyl-3-methylamino-3-deoxy-β-L-arabinopyranosyl)-4-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-3-amino-2,3-dideoxy-D-myo-inositol is a structurally complex aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. Its intricate glycosidic architecture makes it a valuable intermediate for synthesizing novel bioactive compounds and exploring structure-activity relationships. This high-purity chemical is primarily utilized by research institutions and pharmaceutical companies focused on antibiotic development, enzymology studies, and carbohydrate chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel aminoglycoside antibiotics and antimicrobial agents.
• Biochemical Research: Used as a substrate or inhibitor in studies of glycosyltransferases, aminoglycoside-modifying enzymes, and other carbohydrate-processing enzymes.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize antibacterial potency and reduce ototoxicity or nephrotoxicity.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Glycobiology Studies: Investigated for its role in understanding complex carbohydrate recognition and biosynthesis pathways.

Basic Information

Product Name	6-O-(4-C-Methyl-3-methylamino-3-deoxy-β-L-arabinopyranosyl)-4-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-3-amino-2,3-dideoxy-D-myo-inositol
CAS No.	72614-86-9
Molecular Formula	C20H40N4O9
Molecular Weight	480.56 g/mol
Synonyms	4-O-(2-Amino-6-methylamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-6-O-(4-C-methyl-3-methylamino-3-deoxy-β-L-arabinopyranosyl)-3-amino-2,3-dideoxy-D-myo-inositol; 3'''-N-Methylsisomicin; Antibiotic G 52; Antibiotic 6640; 3'''-N-Methylgentamicin C2b; 6'-N-Methylsisomicin; (2R,3R,4R,5R)-2-[[(1S,2S,3R,4S,6R)-4,6-Diamino-3-[[(2R,3S,4R,5S)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]oxy]-2-hydroxycyclohexyl]oxy]-5-methylaminomethyloxane-3,4-diol
EINECS	Contact for details

Quality Control

Our production of 6-O-(4-C-Methyl-3-methylamino-3-deoxy-β-L-arabinopyranosyl)-4-O-(2-amino-6-methylamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-3-amino-2,3-dideoxy-D-myo-inositol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.