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(11R)-11-C-(6-Amino-9H-purin-9-yl)-2,6:8,11-dianhydro-10-O-methyl-4-O-[(E)-1-oxo-2-methyl-2-butenyl]-7-deoxy-α-L-ido-D-lyxo-5-undecoulo-5,9-pyranosonic acid methyl ester CAS NO 72283-61-5
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CAS No.:72283-61-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(11R)-11-C-(6-Amino-9H-purin-9-yl)-2,6:8,11-dianhydro-10-O-methyl-4-O-[(E)-1-oxo-2-methyl-2-butenyl]-7-deoxy-α-L-ido-D-lyxo-5-undecoulo-5,9-pyranosonic acid methyl ester is a complex nucleoside analogue derivative, a key building block in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel antiviral and anticancer agents, particularly in the exploration of modified nucleosides. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation therapeutics. The precise stereochemistry and functional groups make it a critical intermediate for targeted drug discovery programs.
Application
- Pharmaceutical Intermediate: Primary use as a sophisticated building block for the synthesis of experimental antiviral drugs.
- Anticancer Agent Research: Serves as a precursor in the development of novel nucleoside-based chemotherapeutic candidates.
- Biochemical Research: Used in enzymatic studies and as a probe to investigate nucleoside metabolism and related biological pathways.
- Nucleoside Chemistry: A key substrate for organic chemists specializing in the modification of sugar and base moieties to alter biological activity.
- Pre-clinical Drug Development: Employed in the discovery phase for creating libraries of modified nucleosides with potential therapeutic effects.
Basic Information
| Item | Details |
|---|---|
| Product Name | (11R)-11-C-(6-Amino-9H-purin-9-yl)-2,6:8,11-dianhydro-10-O-methyl-4-O-[(E)-1-oxo-2-methyl-2-butenyl]-7-deoxy-α-L-ido-D-lyxo-5-undecoulo-5,9-pyranosonic acid methyl ester |
| CAS No. | 72283-61-5 |
| Molecular Formula | C₂₃H₂₉N₅O₈ |
| Molecular Weight | 503.50 g/mol |
| Synonyms | Methyl (11R)-11-C-(6-amino-9H-purin-9-yl)-2,6:8,11-dianhydro-10-O-methyl-4-O-[(E)-1-oxo-2-methyl-2-butenyl]-7-deoxy-α-L-ido-D-lyxo-5-undecoulo-5,9-pyranosonate; 2',3'-Didehydro-2',3'-dideoxy-4'-C-ethynyl-5-fluorocytidine derivative (related structural class); Modified Adenosine Derivative; Nucleoside Analogue Ester; Purine Nucleoside Intermediate; CAS 72283-61-5; 5-Undecoulo-5,9-pyranosonic acid methyl ester derivative |
| EINECS | Contact for details |
Quality Control
Our (11R)-11-C-(6-Amino-9H-purin-9-yl)-2,6:8,11-dianhydro-10-O-methyl-4-O-[(E)-1-oxo-2-methyl-2-butenyl]-7-deoxy-α-L-ido-D-lyxo-5-undecoulo-5,9-pyranosonic acid methyl ester is produced under strict quality management systems suitable for research and development applications. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and mass spectrometry to confirm identity and purity. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment, ensuring traceability and consistency for your critical research needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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