Description

2-Methylpropenoic acid [(3aS,4S,5R,6R,8Z,10S,11aR)-5-acetoxy-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-4-yl] ester is a high-purity, complex sesquiterpene lactone derivative with significant synthetic utility. This compound serves as a critical advanced intermediate for the research and development of novel bioactive molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis laboratories for its unique structural framework.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, functionalized core.
• Natural Product Analog Synthesis: Serves as a starting material or intermediate for creating analogs of biologically active sesquiterpene lactones.
• Biochemical Probe Development: Utilized in the design of molecular probes to study specific biological pathways and protein interactions.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to produce high-value, specialized chemicals for research markets.
• Academic & Institutional Research: Used in universities and research institutes for exploratory synthetic chemistry and methodological studies.

Basic Information

Item	Details
Product Name	2-Methylpropenoic acid [(3aS,4S,5R,6R,8Z,10S,11aR)-5-acetoxy-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-4-yl] ester
CAS No.	71060-21-4
Molecular Formula	C22H28O8
Molecular Weight	420.46 g/mol
Synonyms	Methacrylic acid, (3aS,4S,5R,6R,8Z,10S,11aR)-5-acetoxy-2,3,3a,4,5,6,7,10,11,11a-decahydro-6-hydroxy-6,10-dimethyl-3-methylene-2,7-dioxocyclodeca[b]furan-4-yl ester; Parthenolide Methacrylate Derivative; 5-Acetoxy-4-methacryloyloxy-6,10-dimethyl-3-methylenedecahydro-2,7-dioxocyclodeca[b]furan-6-ol; Sesquiterpene Lactone Methacrylate Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.