Description

Benzhydryl 7-[[2-(4-hydroxyphenyl)-3-(4-methoxybenzyloxy)-3-oxopropionyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is a sophisticated, high-purity chemical intermediate characterized by its complex bicyclic β-lactam structure. This compound is critical for advanced pharmaceutical synthesis, particularly in the development of next-generation cephalosporin antibiotics. It is primarily sought by R&D laboratories and manufacturers in the global pharmaceutical and fine chemical industries for its role in creating potent, targeted antimicrobial agents.

Application

• Key Intermediate in Cephalosporin Antibiotic Synthesis: Serves as a crucial building block for the production of advanced β-lactam antibiotics.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the design and synthesis of novel antibacterial compounds with improved efficacy and spectrum of activity.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of specific, potent cephalosporin drugs.
• Fine Chemical Synthesis: Utilized in complex multi-step organic syntheses requiring high-purity, specialized intermediates.
• Process Chemistry Development: Aids in optimizing scalable and cost-effective synthetic routes for complex pharmaceutical molecules.

Basic Information

Product Name	Benzhydryl 7-[[2-(4-hydroxyphenyl)-3-(4-methoxybenzyloxy)-3-oxopropionyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS No.	70653-54-2
Molecular Formula	C39H37N5O9S
Molecular Weight	727.81 g/mol
Synonyms	7-[[2-(4-Hydroxyphenyl)-3-(4-methoxybenzyloxy)-3-oxopropionyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester; Diphenylmethyl 7β-[(R)-2-(4-Hydroxyphenyl)-2-[(4-methoxybenzyloxy)formamido]acetamido]-7α-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-1-oxa-1-dethia-3-cephem-4-carboxylate; Cephalosporin intermediate 70653-54-2; 1-Oxa-1-dethia-3-cephem derivative; Benzhydryl ester of a 7α-methoxy cephalosporin acid.
EINECS	Contact for details

Quality Control

Our benzhydryl 7-[[2-(4-hydroxyphenyl)-3-(4-methoxybenzyloxy)-3-oxopropionyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.