Description

[10b,10'b-Bi-10bH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone,2,2',3,3',5a,5'a,6,6',11,11',11a,11'a-dodecahydro-2,2'-dimethyl-3,3'-bis(phenylmethyl)-,(3S,3'S,5aS,5'aS,10bS,10'bS,11aS,11'aS)- is a complex, stereochemically defined heterocyclic compound that serves as a high-value advanced intermediate or building block in sophisticated organic synthesis. Its intricate fused-ring structure makes it a critical component for research and development in pharmaceutical discovery, particularly for targeting complex biological pathways. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or oncological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs due to its complex, three-dimensional scaffold.
• Asymmetric Synthesis: Employed as a chiral auxiliary or template in stereoselective reactions to induce specific stereochemistry in final target molecules.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, dyes, or functional materials requiring specific optical properties.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development in organic synthesis and catalysis.

Basic Information

Item	Details
Product Name	[10b,10'b-Bi-10bH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone,2,2',3,3',5a,5'a,6,6',11,11',11a,11'a-dodecahydro-2,2'-dimethyl-3,3'-bis(phenylmethyl)-,(3S,3'S,5aS,5'aS,10bS,10'bS,11aS,11'aS)-
CAS No.	64947-43-9
Molecular Formula	C40H38N4O4
Molecular Weight	638.76 g/mol
Synonyms	(3S,3'S,5aS,5'aS,10bS,10'bS,11aS,11'aS)-2,2',3,3',5a,5'a,6,6',11,11',11a,11'a-Dodecahydro-2,2'-dimethyl-3,3'-bis(phenylmethyl)-[10b,10'b-bi-10bH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone; DBI-1; Chiral DBI derivative; (S,S)-DBI Tetrone; Pyrazinopyrroloindole tetrone dimer; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, chiral analysis, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, enantiomeric excess, and impurity profiles. We support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.