Description

2-Methylpropenoic acid (1aR,4Z,5aR,8aR,9S,10aS)-10a-acetoxymethyl-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4-hydroxymethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester is a highly functionalized, complex organic ester with a fused polycyclic structure, making it a valuable advanced intermediate for specialized chemical synthesis. Its intricate molecular architecture, featuring multiple reactive sites including an ester, an epoxide, and hydroxyl groups, provides a versatile scaffold for constructing complex target molecules. This compound is primarily sought after by pharmaceutical research and fine chemical organizations engaged in the development of novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of novel drug candidates, particularly in complex natural product synthesis and medicinal chemistry programs.
• Fine Chemical Synthesis: Used as a sophisticated precursor for synthesizing complex organic molecules, fragrances, and other high-value specialty chemicals.
• Agrochemical Research: Acts as an advanced intermediate in the development of new, structurally complex active ingredients for crop protection.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and catalysis due to its challenging, multi-functional structure.
• Material Science Research: Potential use as a monomer or cross-linking agent in the development of novel polymeric materials with specific properties.

Basic Information

Product Name	2-Methylpropenoic acid (1aR,4Z,5aR,8aR,9S,10aS)-10a-acetoxymethyl-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4-hydroxymethyl-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester
CAS No.	62687-46-1
Molecular Formula	C21H26O8
Molecular Weight	406.43 g/mol
Synonyms	Methacrylic Acid, Artemisinin Derivative Ester; 2-Propenoic acid, 2-methyl-, (1aR,4Z,5aR,8aR,9S,10aS)-10a-(acetyloxy)methyl-1a,2,3,5a,7,8,8a,9,10,10a-decahydro-4-(hydroxymethyl)-8-methylene-7-oxooxireno[5,6]cyclodeca[1,2-b]furan-9-yl ester; Artemisinin Methacrylate Derivative; Dihydroartemisinin Methacrylic Ester; Arteannuin B Methacrylate Ester
EINECS	Contact for details

Quality Control

Our production of this high-purity advanced intermediate adheres to stringent quality protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment, ensuring full traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.