Description

(1R,2R)-2-[(1R)-1α-(3-Furanyl)-3,5,6,7,8,8a-hexahydro-8aα-methyl-5-methylene-3-oxo-1H-2-benzopyran-6β-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetic acid methyl ester is a complex, high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities (NCEs) and process development for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly in steroid and terpenoid-related therapeutic areas.
• Organic Synthesis Research: Serves as a sophisticated chiral scaffold for academic and industrial research into new reaction methodologies and asymmetric synthesis.
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for target molecules in pre-clinical and clinical development phases.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and the exploration of novel pharmacophores in drug discovery programs.

Basic Information

Product Name	(1R,2R)-2-[(1R)-1α-(3-Furanyl)-3,5,6,7,8,8a-hexahydro-8aα-methyl-5-methylene-3-oxo-1H-2-benzopyran-6β-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetic acid methyl ester
CAS No.	6488-67-1
Molecular Formula	C29H34O6
Molecular Weight	478.58 g/mol
Synonyms	Methyl (1R,2R)-2-[(1R)-1α-(3-furyl)-3,5,6,7,8,8a-hexahydro-8aα-methyl-5-methylene-3-oxo-1H-2-benzopyran-6β-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetate; 3-Oxoandrosta-4,6-diene-17β-carboxylic Acid Methyl Ester Derivative; (8aS,9R,10aR)-9-[(1R)-1-(3-Furanyl)-3,5,6,7,8,8a-hexahydro-8a-methyl-5-methylene-3-oxo-1H-2-benzopyran-6-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetic acid methyl ester; CAS 6488-67-1
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-[(1R)-1α-(3-Furanyl)-3,5,6,7,8,8a-hexahydro-8aα-methyl-5-methylene-3-oxo-1H-2-benzopyran-6β-yl]-2,6,6-trimethyl-5-oxo-3-cyclohexene-1-acetic acid methyl ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for chiral purity, assay, and related substances are provided and available upon request, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and prolonged exposure to elevated temperatures; appropriate handling and storage conditions are essential to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.