Description

((4S,5S)-(-)-O-[1-Benzyl-1-(5-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)-2-phenylethyl]-dicyclohexyl-phosphinite)(1,5-COD)iridium (I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate is a highly specialized, chiral iridium-based catalyst salt, designed for advanced asymmetric synthesis. This compound matters for its role in enabling highly enantioselective transformations, a critical requirement in the production of fine chemicals and active pharmaceutical ingredients (APIs). It is primarily needed by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel, optically pure compounds.

Application

• Asymmetric Hydrogenation: A key catalyst for the enantioselective reduction of prochiral olefins, imines, and ketones in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Enables the creation of single-enantiomer drug candidates and complex chiral molecules for preclinical and clinical studies.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is essential for bioactivity.
• Fine Chemical Manufacturing: Applied in the synthesis of high-value, complex chiral building blocks and specialty chemicals.
• Methodology Development: Serves as a benchmark or starting point for developing new catalytic asymmetric reactions in academic and industrial research.
• Process Chemistry Optimization: Employed to scale up and optimize enantioselective routes for cost-effective commercial production of chiral substances.

Basic Information

Product Name	((4S,5S)-(-)-O-[1-Benzyl-1-(5-methyl-2-phenyl-4,5-dihydrooxazol-4-yl)-2-phenylethyl]-dicyclohexyl-phosphinite)(1,5-COD)iridium (I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate
CAS No.	583844-38-6
Molecular Formula	C96H90BF24IrNOP
Molecular Weight	~1920.5 g/mol
Synonyms	Iridium(I) (1,5-cyclooctadiene)[(4S,5S)-(-)-O-[1-benzyl-1-(5-methyl-2-phenyl-4,5-dihydro-4-oxazolyl)-2-phenylethyl]dicyclohexylphosphinite] tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; Ir(COD)[(S,S)-f-Binaphane]BArF; Chiral Iridium(I) Phosphinite Complex Salt; Asymmetric Hydrogenation Catalyst (Iridium, f-Binaphane derived); (S,S)-f-Binaphane Ir(COD) BArF Catalyst; [Ir(COD)((S,S)-f-Binaphane)]BArF
EINECS	Contact for details

Quality Control

Our high-value chiral catalysts are produced and handled under strict quality-controlled environments to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis, including chiral purity assessment by HPLC, elemental analysis, and spectroscopic identification (NMR, IR). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and enantiomeric excess. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label or COA. This material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or ambient light may degrade performance. Keep the container sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline or amorphous solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Chiral Purity (HPLC)	≥ 99% e.e.
Elemental Analysis (C,H,N)	Within theoretical ± 0.5%
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.