Description

2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl 4-(chloromethyl)benzoate is a high-purity, advanced pharmaceutical intermediate of significant synthetic importance. This compound serves as a critical building block in the development of novel steroid-based therapeutics and fine chemical synthesis. It is essential for research and manufacturing in the pharmaceutical industry, particularly for organizations developing hormone analogs and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel steroid-based drugs and hormone analogs.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new therapeutic candidates targeting steroid receptors.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for specialized applications.
• API Manufacturing: Serves as a critical raw material in the controlled production of high-value active pharmaceutical ingredients under GMP conditions.
• Biochemical Research: Utilized in studies investigating steroid metabolism, receptor binding, and signal transduction pathways.

Basic Information

Product Name	2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl 4-(chloromethyl)benzoate
CAS No.	571186-61-3
Molecular Formula	C29H35ClO6
Molecular Weight	515.04 g/mol
Synonyms	4-(Chloromethyl)benzoic Acid (8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl Ester; 2-((11β,17β)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl 4-(chloromethyl)benzoate; Steroid-Chloromethylbenzoate Ester Intermediate; 4-(Chloromethyl)benzoyloxymethyl Prednisolone Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl 4-(chloromethyl)benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be incompatible with strong alkali/organic solvent. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.