Description

L-Threonine, N-acetyl-L-threonyl-(αR)-α-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-2-(acetylamino)-3-hydroxy-4-methyl-1-oxopentyl]oxy]-L-leucyl-N,O-dimethyl-, (7→1)-lactone is a complex, cyclic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound's intricate structure, featuring multiple modified amino acid residues and a lactone bridge, makes it a high-value intermediate for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on peptide-based therapeutics, enzyme inhibitors, and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used as a key scaffold or precursor in medicinal chemistry for developing new enzyme inhibitors and receptor modulators.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of peptide lactones.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and contract manufacturing of high-value compounds.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-Threonine, N-acetyl-L-threonyl-(αR)-α-hydroxybenzenepropanoyl-2,3-didehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-2-(acetylamino)-3-hydroxy-4-methyl-1-oxopentyl]oxy]-L-leucyl-N,O-dimethyl-, (7→1)-lactone
CAS No.	568580-02-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic Peptide Lactone 568580-02-9; N-Acetyl-L-threonyl-(αR)-α-hydroxybenzenepropanoyl-dehydro-N-methylalanyl-L-alanyl-N-methyl-L-alanyl-(3R)-3-[[(2S,3R)-2-(acetylamino)-3-hydroxy-4-methyl-1-oxopentyl]oxy]-L-leucyl-N,O-dimethyl-lactone; (7→1)-Lactone derivative of L-Threonine peptide; Complex Threonine Lactone; Peptidic Lactone Intermediate; CAS 568580-02-9
EINECS	Contact for details

Quality Control

Our high-purity peptide derivatives are manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, MS, and NMR to confirm identity and purity, ensuring it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.